There have been a few games which try to break the mold by reversing the traditional role of the player, casting us instead as the villain. "Overlord" has the player controlling an evil army to enslave or put the torch to humanity. "Dungeons" similarly has you creating deadly traps to bring on the demise of dungeon-crawling, loot-seeking heroes. Destroy All Humans put us in the shoes of the harbinger of an alien invasion.
So, the military shooter then? America, f**k yeah. Every game is the same. The player is an American soldier/marine/SEAL and you have to kill lots of Russians/Chinese/N. Koreans/Arabs. Would you play it if the roles were reversed? Would you buy CoD if, instead of being an American shooting Russians, you were a Russian Spetznaz or Chinese Special Forces, shooting and "interrogating" American soldiers? Would you buy CoD if you were a soldier of the Taliban, tasked with wiping out a US Army base? Or if instead of defending the US as in Crysis 2, you were tasked with destroying it?
Would you be upset if a major developer developed such a game? Is the very idea offensive? Does it make no difference to you whatsoever (freedom of the arts for example)? Well?